Yes, that’s EXACTLY what Nora Desmond said in Sunset Boulevard. Don’t believe me? Watch the movie again. And even if it turns out she doesn’t say those words exactly, her face says it all, really. Besides which, the movie is worth seeing again (or for the first time.
For an equally satisfying viewing experience, watch the awesome video on rectal microbicides below this post.
Why a video on rectal microbicides?
Well first of all, why not?!
Butt also… As the rectal microbicide field expands from small Phase I safety studies to larger Phase II safety studies, and eventually efficacy trials, we need appealing materials to explain rectal microbicide clinical trial participation accurately and to engage interested community members in rectal microbicide development.
At the end of October 2013, the Microbicide Trial Network (MTN) launched one such larger study. This Phase II safety trial is called MTN-017. It is testing a rectal microbicide, which is formulated as a gel containing the antiretroviral drug tenofovir. Volunteers consisting of gay men, other men who have sex with men, and transgender women are participating in the study at sites in the United States, Thailand, South Africa, and Peru. You can learn more about the trial here.
In anticipation of the launch of this trial, International Rectal Microbicide Advocates (IRMA), the MTN, and the Population Council released a jointly produced video called “The Rectal Revolution is Here: An Introduction to Rectal Microbicide Clinical Trials."
The video is available in English, Spanish, and Thai on YouTube. It features animation and live action, and includes interviews with researchers, advocates, and a trial participant. It discusses the need for rectal microbicides and the role of clinical trials in developing products that are safe and effective. There’s even a short two-minute version in English.
The video is available as an electronic file for individuals and organizations that want to use it for workshops and educational sessions. Please email IRMA at
to request the video in electronic file format.
There is also a facilitator guide that accompanies the video. Click here for the video's facilitator guide in English. Click here for the Spanish version of the facilitator guide, and click here for the facilitator guide in Thai.
And for a nice overview of the state of affairs in Rectal Microbicides Land, take a look at this previous article. To stay current on all things rectal and the broader HIV prevention landscape, please join the highly active, moderated IRMA listserv by sending an email to