Smoking's pernicious impact worse with HIV Infection

Published 18, Mar, 2016
Author // Guest Authors - Revolving Door

The Body Pro reports smoking leads all preventable causes of death across the world.And it's more deadly in people with HIV than in HIV-negative people

Smoking's pernicious impact worse with HIV Infection

This article by Mark Mascolini from The Center for AIDS Information & Advocacy also appeared in The Body Pro here.  

Summary: Smoking exacts a huge toll on the health of everyone who becomes addicted to nicotine. That toll is greater in people with HIV, and not only because as a group they smoke more than the general population. Research shows that smoking subtracts more years from the life of a middle-aged person with HIV than HIV itself. Nicotine addiction raises the risk of allcause mortality more in HIV-positive smokers than in HIV-negative smokers.  

A nationwide study in Denmark found that HIV-positive smokers run a 6 times higher risk of myocardial infarction than HIV-positive never-smokers, but current smoking only doubled the MI risk in HIV-negative people. 

 Research in HIV-positive and negative men and women in the United States found that HIV-positive smokers who had prior AIDS pneumonia had a 3.5-fold higher risk of lung cancer than HIV-negative smokers. 

Metaanalysis of 18 studies involving more than 625,000 people with HIV found significantly higher rates of smoking-related cancer and infection-related cancer in HIV-positive people than in the general population. 

People who quit smoking enjoy rapid declines in their risk of smoking-related disease. In the US general population, people who quit by age 40 cut their risk of smoking-related death by 90%. 

Analysis of almost 5500 SMART trial participants determined that current HIV-positive smokers had a higher risk of five outcomes than former smokers with HIV: all-cause mortality, AIDS-related disease, major cardiovascular disease, non-AIDS cancer, and bacterial pneumonia. 

 In a large DAD study analysis, cardiovascular disease incidence fell steadily as time since quitting rose. A CDC study of a nationally representative HIV population identified numerous factors independently linked to higher smoking prevalence: younger age, white or black race versus Hispanic ethnicity, less education, incarceration, poverty, noninjection drug use, binge alcohol drinking, major depression, and a viral load above 200 copies/mL. 

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Guest Authors - Revolving Door

Guest Authors - Revolving Door

The Revolving Door is the place where we publish occasional articles by guest writers. If you would like to submit an article for publication, please contact editor Bob Leahy at